FIG 9.

The DC response to influenza infection is specifically associated with symptomatic influenza virus infection in humans. (A to E) The temporal activities of influenza virus response gene expression clusters were measured in blood samples from a cohort of 17 subjects infected with the seasonal influenza virus strain H3N2/Wisconsin. Subjects were split into symptomatic and asymptomatic groups. Activity was defined by the average fold change of genes in the cluster across the subject group. Significant activity (indicated by filled circles) was determined using QuSAGE, with a threshold P of <0.05.