. 2015 Jul 29;89(20):10286–10293. doi: 10.1128/JVI.01438-15

TABLE 2.

Clinical signs and replication of H5N2 and H5N8 viruses in ferrets

Virus	Wt loss^a	Temp increase (°C)^b	No. of animals exhibiting symptoms/total no. of animals examined		Mean nasal titer (log₁₀ EID₅₀/ml) ± SD^e
Virus	Wt loss^a	Temp increase (°C)^b	Sneezing^c	Lethargy^d	Mean nasal titer (log₁₀ EID₅₀/ml) ± SD^e
Pin/WA/40964	1.2 (2/3)	1.4	0/3	1.1 (3/3)	4.2 ± 0.8 (5)
Gyr/WA/41088-6	1.2 (1/3)	1.3	1/3	1 (1/3)	3.1 ± 1 (1)

Percent mean maximum weight loss observed during the first 10 days p.i. The number of ferrets exhibiting weight loss is indicated in parentheses.

Mean maximum temperature increase over baseline (37.5 to 39.7°C) during the first 10 days p.i.

Number of ferrets that exhibited sneezing during the first 10 days p.i.

The relative inactivity index of ferrets during the first 10 days p.i. is presented. The number of ferrets displaying lethargy is indicated in parentheses.

The mean maximum nasal wash titer is expressed as log₁₀ EID₅₀/ml; the day postinoculation is indicated in parentheses. The limit of detection was 1.5 log₁₀ EID₅₀/ml.