FIG 2.
PrPSc deposition pattern in the brains of Syrian golden hamsters (SGH) infected with WST and CKY CWD. Brain sections from CKY CWD (A, D, G, B, E, H, and K), WST CWD (C, F, I, J, and L), and mock (M, N, and O) infections in SGH were stained for PrPSc by IHC (brown deposit) or stained with hematoxylin and eosin (A, D, G, J, M, N, and O). Brain tissue was from the second (CKY CWD) and third (WST CWD) serial passages in SGH. VC, visual cortex; M, motor cortex; Cg, cingulate cortex; S1, somatosensory cortex; Pir, piriform cortex; HC, hippocampus; SC, superior colliculus; SNR, substania nigra; RN, red nucleus; MG, medial geniculate nucleus; VPM, ventral posterior thalamic nucleus; IPR, interpedunclar nucleus; PN, pretectal nucleus; ZI, zona incerta; H, hypothalamic nuclei; AM, amygdala; Rt, reticular formation; CPu, caudate-putamen; GP, globus pallidum; LS, lateral septal nucleus; MS, medial septal nucleus; ic, internal capsule; cc, corpus callous; LV, lateral ventricle; 3, third ventricle.