TABLE 3.
Adaptation of HY and DY TME from SGH to HPrP7752KO mice
Serial passage | HY TME |
DY TME |
||
---|---|---|---|---|
Mean incubation period (days) ± SEM | A/Ia | Mean incubation period (days) ± SEM | A/Ia | |
1 | 46 ± 0.2 | 5/5 | 116 ± 2.6 | 6/6 |
2 | 51 ± 0.4 | 8/8 | 119 ± 1.5 | 10/10 |
3 | 58 ± 1.7 | 7/7 | 146 ± 5.1 | 7/7 |
4 | 57 ± 1.8 | 6/6 | 140 ± 0.8 | 9/9 |
A/I, number of animals affected by prion disease versus the total number inoculated.