FIG 6.

Immunohistochemical analysis of mouse brains; virus antigens in CT-2A-Fluc glioma tissue were measured from brain samples collected 5 days post-i.p. virus injection. (A) Tumor mass of SFV4-miRT124; (B) magnification of the inset marked in panel A. (C and D) Results in VA7-EGFP-treated mice (C) and PBS-treated mice (D). (E and F) Detection of virus replication in the brain and spinal cord following i.p. injection of SFV4 miRT124. Samples were collected from a mouse suffering from neurological symptoms (E) and an asymptomatic mouse (F).