Fig. 4.
Metabolites showing an altered content in a prohibitin-dependent manner. (A) S-line plot from the O-PLS-DA modelling (1 + 1 + 0 PCs, R2X = 0.619, R2Y = 0.98 and Q2 = 0.948) of the 1H NMR data set from young adult wild type treated with RNAi targeting either phb-1 or phb-2. (B) Relative abundances of the metabolites, based on a characteristic bin, displaying an altered content in a prohibitin-dependent manner (t-test, P-value < 0.05). Similar results were obtained for phb-1/2(RNAi) treated worms.