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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Expert Opin Pharmacother. 2015 Mar 24;16(7):1091–1098. doi: 10.1517/14656566.2015.1026256
Drug Name Oritavancin
Phase Completed Phase III trials
Indication Acute bacterial skin and skin structure infections
Pharmacology description/ mechanism of action Semi-synthetic lipoglycolipopeptide, bactericidal, disrupts cell membrane and inhibits the transglycosylation and transpeptidation steps of cell wall synthesis in a dose-dependent manner
Route of administration Intravenous
Chemical Structure graphic file with name nihms723681t1.jpg
Pivotal Trial(s) SIMPLIFI31
SOLO I29
SOLO II28