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. 2015 Sep 23;13:80. doi: 10.1186/s12915-015-0186-5

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© Rußmayer et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Differential regulation of central carbon metabolism comparing methanol/glycerol- and glucose-grown cells. Visualization of changes in transcript (square, upper symbol), protein (square, lower symbol), and metabolite (oval) levels. Red: up-regulation on methanol/glycerol; blue: down-regulation on methanol/glycerol; gray: not differentially regulated; white/no symbol: not measured. Criteria for up-/down-regulation of transcript, protein, and metabolite levels are described in the Methods section