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. Author manuscript; available in PMC: 2015 Sep 23.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2013 Jun 28;3(1):69–81. doi: 10.1002/wdev.122

Figure 6. Loss-of-function mosaic analysis of neuronal temporal identity.

Figure 6

(A–D) In the wild-type adAL lineage, the VA7l and VA2 uniglomerular PNs are born sequentially (A), as twin-spot MARCM labeling (B) shows pairing of the smallest VA2-containing NB clone (C) with the VA7l-targeting PN (D).

(E–H) By contrast, the Kr mutant single-neuron GMC clone (green) paired with the equivalent VA2-containing wild-type NB clone (magenta) redundantly innervates the VA2 glomerulus (E–G). This chronologically abnormal phenotype argues for the acquisition of the next VA2 temporal cell fate by the prospective VA7l PN (H). Scale bar: 10 μm.