Table 4.
Results of PDON-driven search in response to expert competency questions. In contrast to PubMed queries, PDON-driven search in SCAIView generated a list of entities that precisely answer the competency questions
| Competency question | Entities | PubMed ID |
|---|---|---|
| Return all literature references mentioning drugs used to treat 'freezing' in PD. | Levodopa | 6858781, 16222436, 12217618, 15262734 |
| Selegiline | 12112107, 22324564, 18937611 | |
| Amantadine | 23185280, 24057149 | |
| Atomoxetine | 19361809 | |
| L-threo-DOPS | 6337612, 8174332 | |
| Droxidopa | 23242741, 7834960 | |
| Manganese | 8351000 | |
| Galantamanie | 23130517, 18427456 | |
| Methylphenidate | 23076544 | |
| Deprenyl | 11425939 | |
| Rasagiline | 21389939 | |
| Return literature references containing genes that provide resistance to PD in the animal model MPTP. | Nos1 | 12490535, 8643444 |
| Nos2 | 10581083 | |
| Sod1 | 1578260 | |
| Ccl2 | 17258864 | |
| Mcpt1 | 17258864 |