Table 1.
Prevalence of allelic combinations and repetitive motifs in dhfr gene among Plasmodium vivax isolates in Indonesia
| Type | Prevalence in malaria-endemic areas (%) | ||||
|---|---|---|---|---|---|
| Papua | Lampung | Purworejo | Sumba | Mataram | |
| Allelic combination | |||||
| 58R/117N | 11.8 (4/34) | 96.3 (26/27) | 60 (6/10) | 0 (0/60) | 0 (0/28) |
| 58R/61M/117N | 2.9 (1/34) | 11.1 (3/27) | 0 (0/10) | 0 (0/60) | 0 (0/28) |
| 57L/58R/61M/117T | 61.8 (21/34) | 0 (0/27) | 10 (1/10) | 3.3 (2.60) | 0 (0/28) |
| Repetitive motifs GGDN (units) | |||||
| Type A = three units | 100 (34/34) | 66.7 (18/27) | 100 (10/10) | 85.7 (24/28) | 92.9 (26/28) |
| Type B = two units | 0 (0/34) | 33.3 (9/27) | 0 (0/10) | 14.3 (4/28) | 7.1 (2/28) |