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. 2015 Sep 23;10(9):e0138652. doi: 10.1371/journal.pone.0138652

Table 2. Associations between polymorphisms in the APOA4-APOA5-ZNF259-BUD13 gene cluster and TG levels in 5347 Chinese Han participants.

SNP Position a Near gene Genotype (major/minor) MAF b Effect size (s.e.m.) c P d
rs17119975 116139767 BUD13 T/C 0.232 -0.089 (0.017) 1.79×10−9
rs964184 116154127 ZNF259 C/G 0.226 0.117 (0.024) 9.28×10−18
rs4417316 116157511 ZNF259 C/T 0.280 -0.107 (0.022) 3.34×10−13
rs6589566 116157633 ZNF259 A/G 0.226 0.125 (0.019) 1.96×10−18
rs651821 116167789 APOA5 T/C 0.262 0.170 (0.014) 2.35×10−32
rs7396835 116189238 APOA4 C/T 0.339 0.100 (0.020) 3.86×10−12

aChromosomal positions are based on the NCBI Build 36 of the genome.

bMAF, minor allele frequency.

cThe minor allele is the effect allele, and the major allele is the reference allele.

dThe P values for the effects of genotypes on plasma TG levels were assessed by multiple linear regression models with adjustment for age, sex and BMI.