Table 4. Associations of the five TG-associated SNPs on the APOA4-APOA5-ZNF259-BUD13 gene cluster with CHD risk in a Chinese Han population.
| Genotype | CHD cases, n (%) | Controls, n (%) | Adjusteda OR (95% CI) | Adjusted a P | |
|---|---|---|---|---|---|
| rs17119975 | |||||
| TT | 371 (60.0) | 393 (59.2) | 1.00 | ||
| TC | 259 (38.3) | 258 (38.9) | 1.06 (0.85–1.33) | 0.59 | |
| CC | 10 (1.7) | 13 (1.9) | 0.82 (0.47–1.88) | 0.63 | |
| rs4417316 | |||||
| CC | 345 (55.8) | 366 (55.1) | 1.00 | ||
| CT | 228 (36.9) | 245 (37.0) | 0.99 (0.78–1.25) | 0.91 | |
| TT | 45 (7.3) | 52 (7.9) | 0.92 (0.60–1.41) | 0.69 | |
| rs6589566 | |||||
| AA | 329 (53.3) | 355 (53.5) | 1.00 | ||
| AG | 272 (44.1) | 291 (43.8) | 1.01 (0.81–1.26) | 0.94 | |
| GG | 16 (2.6) | 18 (2.7) | 0.96 (0.48–1.91) | 0.91 | |
| rs651821 | |||||
| TT | 702(53.6) | 683(53.2) | 1.00 | ||
| TC | 501(38.3) | 492(38.3) | 1.02(0.85–1.21) | 0.87 | |
| CC | 106(8.1) | 110(8.5) | 1.13(0.88–1.35) | 0.44 | |
| rs7396835 | |||||
| CC | 172 (27.9) | 186 (28.1) | 1.00 | ||
| CT | 379 (61.4) | 406 (61.1) | 1.01 (0.79–1.30) | 0.94 | |
| TT | 66 (10.7) | 72 (10.8) | 0.99 (0.67–1.47) | 0.96 |
aData were calculated by a logistic regression analysis with adjustment for age, sex, smoking and BMI.