Table 2.

Complications and adverse events^*

	Alteplase (N = 25)	Fingolimod + Alteplase (N = 22)	P value
Complications
Deaths	0 (0)	0 (0)
Myocardial infarctions	0 (0)	0 (0)
Recurrent strokes	0 (0)	0 (0)
Cerebral hernia	1 (4)	0 (0)	1.00
Hemorrhage of digestive tract	3 (12)	1 (5)	0.61
Fever (>38 °C)	5 (20)	5 (23)	1.00
Event
All events
At least one adverse event	8 (32)	6 (27)	0.76
Any adverse event leading to discontinuation	0 (0)	0 (0)
Any serious adverse event	0 (0)	0 (0)
Frequent or special-interest adverse events
Suspected lung infection	3 (12)	3 (14)	1.00
Urinary tract infection	2 (8)	2 (9)	1.00
Herpes virus infection	0 (0)	0 (0)
Abnormal laboratory liver-function test	0 (0)	0 (0)
Gastrointestinal disorders	0 (0)	0 (0)
Leukopenia	0 (0)	0 (0)
Lymphopenia	0 (0)	0 (0)
Bradycardia	0 (0)	0 (0)
Atrioventricular block	0 (0)	0 (0)
Macular edema	0 (0)	0 (0)

^*Data are n (%).