Table 2. Set of 13 representative metalloproteases of the MA Clan.
MEROPS Sub-clan | MEROPS Family | Protein | PDB ID | CATH Superfamily | SCOP Family |
---|---|---|---|---|---|
MA(E) | M4 | Thermolysin | 1L3F | 1.10.390.10; 3.10.170.10 | 55490 |
MA(E) | M1 | Leukotriene A4 hydrolase | 1H19 | 1.10.390.10 | 64338 |
MA(E) | M3 | Neurolysin | 1I1I | 1.10.1370.10; 3.40.390.10; 1.20.1050.40 | 55505 |
MA(E) | M32 | Carboxypeptidase Pfu | 1KA4 | n.a. | 55505 |
MA(E) | M2 | Angiotensin Converting Enzyme | 1O8A | n.a. | 55505 |
MA(E) | M27 | Botulinum neurotoxin type A | 3BON | n.a. | 55512 |
MA(M) | M7 | Extracellular small neutral protease | 1C7K | 3.40.390.10 | 55487 |
MA(M) | M35 | Peptidyl-Lys metalloendopeptidase | 1G12 | 3.40.390.10 | 55487 |
MA(M) | M8 | Leishmanolysin | 1LML | 3.90.132.10; 3.10.170.20; 2.30.34.10; 2.10.55.10 | 55499 |
MA(M) | M10(A) | Interstitial collagenase | 1CGE | 3.40.390.10 | 55528 |
MA(M) | M10(B) | Serralysin | 1AKL | n.a.; 2.150.10.10 | 55508 |
MA(M) | M12(A) | Astacin | 1AST | 3.40.390.10 | 55516 |
MA(M) | M12(B) | Snake venom metalloproteinase adamalysin-2 | 1IAG | 3.40.390.10 | 55519 |