Table 2. Comparison of the clinical symptoms and laboratory findings of HFMD patients with different enterovirus infection.
| Characterics | CA6 (n = 152) | CA10 (n = 35) | CA16 (n = 42) | EV71 (n = 144) | Total (n = 472) |
|---|---|---|---|---|---|
| Clinical symptoms | |||||
| Fever (%) | 137(90.13) | 33(94.29) | 36(85.71) # | 137(95.14) | 412(87.29) |
| Oral ulcer (%) | 140(92.11) | 32(91.43) | 39(92.86) | 129(89.58) | 406(86.02) |
| No rash (%) | 2(1.32) | 0(0) | 2(4.76) | 2(1.39) | 7(1.48) |
| Cough (%) | 31(20.39) | 5(14.29) | 11(26.19) | 20(13.89) | 79(16.74) |
| Vomiting (%) | 27(17.76) | 10(28.57) | 12(28.57) | 38(26.39) | 102(21.61) |
| Headache (%) | 0(0) | 0(0) | 1(2.38) | 2(1.39) | 4(0.85) |
| Startle (%) | 20(13.16) # | 7(20.00) | 9(21.43) | 34(23.61) | 80(16.95) |
| Febrile seizure (%) | 6(3.95) | 3(8.57) # | 0(0) | 1(0.69) | 15(3.18) |
| Limb shaking (%) | 3(1.97) # | 1(2.86) # | 3(7.14) | 26(18.06) | 36(7.63) |
| Neck rigidity (%) | 0(0) # | 0(0) | 0(0) | 5(3.47) | 5(1.06) |
| Laboratory findings | |||||
| WBC(×10 9 /L) | 9.69±4.15 | 9.44±3.69 | 10.12±4.01 | 9.33±2.92 | 9.54±3.67 |
| WBC>12×10 9 /L (%) | 38(25.00) | 9(25.71) | 11(26.19) | 25(17.36) | 95(20.13) |
| ALT(U/L) | 12.55±16.35 | 9.97±4.40 | 11.00±6.05 | 12.40±24.84 | 13.52±32.49 |
| ALT>40 (%) | 3(1.97) | 0(0) | 0(0) | 4(2.78) | 11(2.33) |
| AST(U/L) | 24.45±11.82 | 22.40±7.14 | 24.12±7.14 | 23.66±17.10 | 25.08±24.89 |
| AST>40 (%) | 6(3.95) | 1(2.86) | 2(4.76) | 8(5.56) | 23(4.87) |
| CK-MB(U/L) | 44.66±26.00 # | 41.97±28.13 | 41.73±22.85 | 37.92±23.39 | 41.56±27.72 |
| CK-MB>40 (%) | 58(38.16) | 8(22.86) | 17(40.48) | 41(28.47) | 143(30.3) |
| CRP>40 (%) | 22(14.47) # | 11(31.43) # | 1(2.38) | 2(1.39) | 45(9.53) |
| CTnI abnormality (%) | 9(5.92) | 2(5.71) | 5(11.90) # | 4(2.78) | 26(5.51) |
| CSF WBC>10×10 6 /L (%) | 1/16(6.25) # | 0/8(0) # | 0/8(0) # | 52/63(82.54) | 61/108(56.48) |
| CSF Pro>500U/L (%) | 2/16(12.50) | 0/8(0) | 1/8(12.50) | 11/63(17.46) | 17/108(15.74) |
#: Compared with EV71 infection group, P < 0.05.