Table 2.

Crude and adjusted HRs for incident fracture

	A. All fracture sites
	Person-years (n1)	Crude HR (95% CI)	Adjusted HR2 (95% CI)	Person-years (n1)	Crude HR (95% CI)	Adjusted HR2 (95% CI)
Age-group	Males			Females
0–19 years	112,460 (30,623)	1.14 (1.01–1.29)4	1.14 (1.01–1.29)4	98,851 (26,525)	1.35 (1.12–1.63)5	1.35 (1.12–1.62)5
20–29 years	132,639 (34,860)	1.42 (1.24–1.63)4	1.40 (1.22–1.60)4	113,175 (32,587)	1.76 (1.43–2.17)4	1.72 (1.39–2.12)4
30–39 years	202,109 (42,878)	1.55 (1.36–1.77)6	1.50 (1.31–1.71)6	158,358 (29,776)	1.91 (1.61–2.26)6	1.77 (1.49–2.12)6
40–49 years	224,241 (31,804)	1.86 (1.65–2.11)6	1.78 (1.57–2.01)6	153,547 (19,337)	2.03 (1.73–2.39)6	1.82 (1.53–2.16)6
50–59 years	168,936 (20,957)	2.07 (1.78–2.41)6	1.97 (1.69–2.31)6	106,941 (13,582)	1.78 (1.51–2.11)6	1.69 (1.42–2.01)6
60–69 years	117,089 (14,077)	2.18 (1.79–2.65)6	2.00 (1.63–2.45)6	84,277 (11,235)	1.95 (1.65–2.30)6	1.76 (1.49–2.10)6
70–89 years	111,447 (12,268)	1.64 (1.35–1.99)6	1.55 (1.27–1.89)6	106,952 (13,757)	1.79 (1.58–2.03)6	1.69 (1.49–1.92)6

	B. Hip fracture
	Person-years (n1)	Crude HR (95% CI)	Adjusted HR3 (95% CI)	Person-years (n1)	Crude HR (95% CI)	Adjusted HR2 (95% CI)
Age-group	Males			Females
0–29 years	263,584 (65,483)	2.01 (0.99–4.10)	1.90 (0.92–3.93)	218,777 (59,112)	4.71 (1.45–15.28)4	4.69 (1.44–15.23)4
30–39 years	211,666 (42,878)	3.42 (1.25–9.32)4	3.38 (1.24–9.25)4	162,501 (29,776)	5.63 (2.25–14.11)6	4.16 (1.52–11.43)5
40–49 years	234,658 (31,804)	3.59 (1.86–6.91)6	2.56 (1.24–5.29)4	158,903 (19,337)	4.55 (1.75–11.85)5	2.10 (0.65–6.78)
50–59 years	175,743 (20,957)	3.64 (2.07–6.41)6	3.23 (1.79–5.84)6	111,739 (13,582)	5.06 (2.80–9.14)6	4.38 (2.31–8.31)6
60–69 years	120,950 (14,077)	5.64 (3.55–8.97)6	5.21 (3.2–8.47)6	89,406 (11,235)	4.22 (2.73–6.56)6	3.21 (2.00–5.16)6
70–89 years	115,389 (12,268)	1.99 (1.43–2.78)6	1.71 (1.21–2.4)5	116,740 (13,757)	2.6 (2.13–3.18)6	2.34 (1.91–2.87)6

¹Based on age at study entry.

²Adjusted for exposure to steroid medication, history of prior fracture, and presence of chronic kidney disease.

³Adjusted for exposure to steroid medication, history of prior fracture, presence of chronic kidney disease, and hypothyroidism.

⁴P < 0.05.

⁵P < 0.01.

⁶P < 0.001.