Table 3. MICs for standard antibacterial drugs as determined by the MABA assay.

	MIC (μM) a
Standard drugs	ΔglpX	WT Mtb H37Rv
RMP	0.023 ± 0.005	0.053 ± 0.007
INH	0.479 ± 0.010	0.476 ± 0.009
MET	> 512	> 512
CAP	1.72 ± 0.061	1.89 ± 0.095
SM	0.48 ± 0.097	0.82 ± 0.083
PA-824	0.48 ± 0.027	0.16 ± 0.007
OPC-67683	0.006 ± 0.001	0.009 ± 0.001

^a Reported MIC values are an average (± standard deviation) of 6 independent assays. Although the MIC of PA-824 for the ΔglpX strain is significantly higher (about 3–4 fold) than that observed for WT Mtb strain, it is within the normal MIC range of 0.015 to 0.5 μM.