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CCN family involvement in human MSC differentiation
aCCN expression promotes (
) or inhibits (
) MSC or committed progenitor differentiation into osteoblast, chondrocyte or adipocyte
bLoss of CCN expression (
) in undifferentiated MSCs upon differentiation to osteoblast, chondrocyte or adipocyte, as described by Schutze et al. (2005)
