Table 2. Echocardiographic and invasive parameters prior to and after the treatment (n=25).
| Pre-treatment | Post-treatment | p | |
|---|---|---|---|
| Clinical parameter | |||
| Functional class (III/IV) | 18/1 | 6/0 | 0.02 |
| 6MWD (m) | 390±80 | 453±101 | 0.02 |
| BNP concentration (pg/ml) | 494±123 | 270±68 | 0.01 |
| LogBNP | 2.3±0.6 | 1.8±0.7 | 0.01 |
| Echocardiographic parameters | |||
| RV basal dimension (cm) | 3.8±0.8 | 3.6±0.7 | 0.31 |
| RV longitudinal dimension (cm) | 8.1±0.8 | 8.5±0.9 | 0.02 |
| RV end-diastolic area (cm2) | 30.5±7.9 | 29.9±11.2 | 0.77 |
| RV end-systolic area (cm2) | 24.4±6.9 | 22.4±10.9 | 0.34 |
| RA size (cm2) | 25.7±8.5 | 23.8±9.1 | 0.25 |
| RVFAC (%) | 20.5±7.4 | 28.3±11.7 | <0.01 |
| TAPSE (cm) | 1.3±0.5 | 1.6±0.4 | <0.01 |
| LS, global RV (%) | -12.4±4.6 | -15.9±4.7 | <0.01 |
| LS, RV free wall (%) | -14.0±5.1 | -18.0±5.2 | <0.01 |
| Cardiac catheterization | |||
| Mean PA pressure (mmHg) | 53.9±12.8 | 46.5±15.9 | 0.03 |
| CI (l/min/m2) | 2.4±1.1 | 3.1±1.1 | 0.01 |
| PVR (WU) | 11.3±5.1 | 5.7±2.4 | <0.01 |
6MWD: 6-minute walking distance, BNP: B-type natriuretic peptide, RV: right ventricle, RA: right atrium, RVFAC: right ventricular fractional area change, TAPSE: tricuspid annular plane systolic excursion, LS: longitudinal strain, PA: pulmonary artery, CI: cardiac index, PVR: pulmonary vascular resistance, WU: wood units