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. 2015 Apr 28;54(10):1043–1055. doi: 10.1007/s40262-015-0271-5

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Concentration–time profiles (mean ± standard deviation) for the sum of enzalutamide plus N-desmethyl enzalutamide after a single oral dose of enzalutamide 160 mg in male subjects: a subjects with mild hepatic impairment (Child–Pugh Class A; n = 8) and the age- and BMI-matched control subjects with normal hepatic function (n = 8); b subjects with moderate hepatic impairment (Child–Pugh Class B; n = 6) and the age- and BMI-matched control subjects with normal hepatic function (n = 6). BMI body mass index