Table 1.
Demographic features
|
Peak-PRA 0%-30% |
Peak-PRA 31%-60% |
Peak-PRA > 60% |
||||
| Steroid | No steroid | Steroid | No steroid | Steroid | No steroid | |
| (n = 25218) | (n = 7399) | (n = 3495) | (n = 850) | (n = 4966) | (n = 923) | |
| Donor factors | ||||||
| Age | 38 ± 17 | 39 ± 17b | 37 ± 17 | 38 ± 18 | 35 ± 15 | 35 ± 16 |
| Gender (M/F) % | 59/41 | 59/41 | 60/40 | 57/43 | 60/40 | 66/34b |
| Death from CVA (%) | 42 | 40a | 38 | 41a | 36 | 35a |
| ECD kidney (%) | 18 | 20d | 15 | 22d | 8 | 10 |
| DCD kidney (%) | 7.7 | 9.1d | 6.1 | 7.6 | 6.7 | 8.1 |
| Recipient factors | ||||||
| Age (yr) | 51 ± 13 | 53 ± 13d | 37 ± 17 | 38 ± 17 | 47 ± 13 | 49 ± 13 |
| Gender (M/F) % | 66/34 | 67/33 | 51/49 | 51/49 | 37/63 | 34/66 |
| African American | 30 | 26d | 28 | 28 | 33 | 31 |
| Diabetes | 33 | 36d | 29 | 34b | 25 | 28 |
| Pre-transplant dialysis (%) | 91 | 88d | 89 | 84d | 91 | 91 |
| Dialysis duration (mo) | 45 ± 34 | 44 ± 35a | 49 ± 42 | 47 ± 42 | 61 ± 51 | 59 ± 52 |
| Previous transplant (%) | 7.3 | 4.6d | 21.8 | 14.6d | 44.2 | 37.9d |
| HLA mismatches | 3.7 ± 1.8 | 3. 7 ± 1.9 | 3.5 ± 2.0 | 3.1 ± 2.0a | 3.1 ± 2.0 | 3.0 ± 2.0 |
| Transplant- related factors | ||||||
| Cold ischemia (h) | 18.1 ± 8.1 | 18.8 ± 8.0d | 18.3 ± 7.9 | 20.8 ± 10.2d | 18.4 ± 8.1 | 19.3 ± 8.2b |
| Delayed graft function (%) | 24.4 | 19.5d | 22.9 | 19.6a | 26 | 20.8b |
P value is for steroid vs no steroid:
a
P < 0.05,
b
P < 0.01;
d
P < 0.001. CVA: Cerebrovascular accident; DCD: Donation after cardiac death; ECD: Expanded criteria donor; HLA: Human leukocyte antigen; PRA: Panel reactive antibody.