Table 1. Cohorts included in the study.
| Cohort | Number of samples | Duos from informative nuclear families | Informative duos | Duos from families with >1 child |
|---|---|---|---|---|
| Carlantino, Italy | 630 | 6 (2) | 29 (11) | 53 (23) |
| French Canadians | 477 | 106 (29) | 158 (50) | 218 (80) |
| Friuli Venezia Giulia, Italy | 1,236 | 13 (4) | 72 (26) | 160 (70) |
| Korcula, Croatia | 897 | 0 (0) | 7 (3) | 34 (17) |
| Netherlands Twin Registry | 2,729 | 298 (96) | 398 (130) | 889 (379) |
| ORCADES, Orkney, Scotland | 2,215 | 48 (15) | 118 (40) | 252 (109) |
| Queensland Twin Registry (QTR370) | 3,754 | 890 (239) | 1,310 (323) | 1,441 (389) |
| Queensland Twin Registry (QTR610) | 7,364 | 1,283 (403) | 1,337 (420) | 2,898 (1202) |
| Queensland Twin Registry (QTRCoreExome) | 4,444 | 234 (75) | 329 (106) | 781 (332) |
| Val Borbera, Italy | 1,664 | 30 (9) | 72 (26) | 266 (123) |
| Vis, Croatia | 960 | 0 (0) | 11 (4) | 37 (17) |
| Total | 3,036 (910) | 4,253 (1268) | 7,688 (3003) | |
| Total analysed | 2,889 (866) | 3,823 (1132) | 6,011 (2305) |
The three rightmost columns show the number of maternal meioses for which we had age data, followed by the number of families in parentheses. The total number analysed excludes the cohorts (or, for the rightmost column, family configurations within a cohort) with fewer than 20 meioses. The SNP chips used, number of SNPs and sample sizes for paternal meioses are given in Supplementary Table 1.