Table 2.
Capture mAb | First round capture | 4B3 Depleted Second round capture |
b12 Depleted Second round capture |
2F5 Depleted Second round capture |
||||
---|---|---|---|---|---|---|---|---|
Input: 1000 ng | Input: 399 ng | Input: 491 ng | Input: 526 ng | |||||
ng/p24 | % input | ng/p24 | % input | ng/p24 | % input | ng/p24 | % input | |
4B3 | 601 | 60.1 | 0.8 | 0.2 | 457.6 | 93.2 | 373.5 | 71.0 |
2F5 | 474 | 47.4 | 92.2 | 23.1 | 206.2 | 42.0 | 4.2 | 0.8 |
b12 | 509 | 50.9 | 375.9 | 94.2 | 1.0 | 0.2 | 260.4 | 49.5 |
The header row describes the input virus, either total virus for the first round capture (1000 ng/p24) or the collected unbound fraction following first round depletion with 4B3 (399 ng/p24), b12 (491 ng/p24) or 2F5 (526 ng/p24)
Italics indicate the values after first round capture