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In these light microscopic images, we see the protective effects of hypothermic intervention followed by slow rewarming (a) versus the damaging effects associated with hypothermia followed by rapid rewarming (b) In both a and b, the damaged immunoreactive axons are labeled with arrows, with a striking demonstration of reduced axonal burden in a versus b. Reprinted with permission from [152], copyright Mary Ann Liebert, Inc., 2009.
