Table 1.
LAMP3 expression and clinicopathological characteristics in ESCC.
| Variable | Cases | LAMP3 Expression | p Value a | |
|---|---|---|---|---|
| Low (%) | High (%) | |||
| Gender | - | - | - | 0.304 |
| Male | 110 | 51 (46.4) | 59 (53.6) | - |
| Female | 47 | 26 (55.3) | 21 (44.7) | - |
| Age (years) | - | - | - | 0.003 |
| <57 | 73 | 45 (61.6) | 28 (38.4) | - |
| ≥57 | 84 | 32 (38.1) | 52 (61.9) | - |
| Tumor Size (cm) | - | - | - | 0.063 |
| <3.9 | 76 | 32 (42.1) | 44 (57.9) | - |
| ≥3.9 | 77 | 44 (57.1) | 33 (42.9) | - |
| Tumor Location | - | - | - | 0.063 |
| Upper | 12 | 2 (16.7) | 10 (83.3) | - |
| Middle | 102 | 52 (51.0) | 50 (49.0) | - |
| Lower | 43 | 23 (53.5) | 20 (46.5) | - |
| Histologic Grade | - | - | - | 0.344 |
| G1 | 34 | 16 (47.1) | 18 (52.9) | - |
| G2 | 79 | 43 (54.4) | 36 (45.6) | - |
| G3 | 44 | 18 (40.9) | 26 (59.1) | - |
| T Status | - | - | - | 0.749 |
| T1–T2 | 31 | 16 (51.6) | 15 (48.4) | - |
| T3–T4 | 126 | 61 (48.4) | 65 (51.6) | - |
| Lymph Node Metastasis | - | - | - | 0.134 |
| N0 | 68 | 38 (55.9) | 30 (44.1) | - |
| N1 | 89 | 39 (43.8) | 50 (56.2) | - |
| TNM Stage | - | - | - | 0.095 |
| I–IIa | 59 | 34 (57.6) | 25 (42.4) | - |
| IIb–IV | 98 | 43 (43.9) | 55 (56.1) | - |
| Cigarette Smoking | - | - | - | 0.155 |
| Never | 53 | 30 (56.6) | 23 (43.4) | - |
| Smoking | 101 | 45 (44.6) | 56 (55.4) | - |
| Alcohol | - | - | - | 0.018 |
| Never | 92 | 52 (56.5) | 40 (43.5) | - |
| Drinking | 62 | 23 (37.1) | 39 (62.9) | - |
a Pearson chi-squared test.