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. 2015 Aug 10;16(8):18564–18579. doi: 10.3390/ijms160818564

Figure 1.

Figure 1

VM structure and endothelial-dependent vessels in colon cancer. (A) VM channel (red arrow) lined with tumor cells and containing red blood cells (H&E staining, ×400); (B) Endothelial-dependent vessel lined with flat endothelium cells (green arrow) (H&E staining, ×400); (C) VM channel formed by tumor cells was negative for CD34; the one lined with a base membrane-like structure was positive for PAS (red square frame); and the endothelial-dependent vessel was both positive for CD34 and PAS (black square frame) (CD34/PAS double staining, ×200).