Table 1.
Cloned R-genes from plant species.
| Species a | R-Gene | Accession ID | Domain b | Class | Chr | Disease c | Avr Gene | Pathogen c | Reference |
|---|---|---|---|---|---|---|---|---|---|
| T. aestivum (wheat) | Lr10 | AAQ01784 | CNL | NBS | 1A | Leaf rust | AvrLr10 | P. triticina | [23] |
| Lr1 | ABS29034 | CNL | NBS | 5D | Leaf rust | Avr1 | P. triticina | [24] | |
| Pm3b | AAQ96158 | CNL | NBS | 1A | Powdery mildew | AvrPm3b | B. graminis | [25] | |
| Sr33 | AGQ17390 | CNL | NBS | 1D | Stem rust | P. graminis | [26] | ||
| Sr35 | AGP75918 | CNL | NBS | 3A | Stem rust | P. graminis | [27] | ||
| Lr21 | AAP74647 | NL | NBS | 1D | Leaf rust | AvrLr21 | P. triticina | [28] | |
| Cre3 | AAC05834 | NL | NBS | 2D | Cereal cyst | H. avenae | [29] | ||
| Cre1 | AAM94164 | NL | NBS | 2B | Cereal cyst | H. avenae | [30] | ||
| Yr10 | AAG42168 | CNL | NBS | 1B | Stripe rust | P. striiformis | [31] | ||
| Stpk-V (Pm21) | AEF30547 | STK | Oth-R | 6V | Powdery mildew | B. graminis | [32] | ||
| Lr34 | ACN41354 | ABC transporter | Oth-R | 7D | Leaf rust, Powdery mildew, Stripe rust | P. triticina; P. striiformis; B. graminis | [33] | ||
| Yr36 | ACF33195 | Kinase-START | Oth-R | 6B | Stripe rust | P. striiformis | [34] | ||
| H. vulgare (barley) | Mla6 | CAC29241 | CNL | NBS | 1 | Powdery mildew | AvrMla6 | B. graminis | [35] |
| Mla1 | AAG37356 | CNL | NBS | 1 | Powdery mildew | AvrMla1 | B. graminis | [36] | |
| Mla13 | AAO16014 | CNL | NBS | 1 | Powdery mildew | AvrMla13 | B. graminis | [37] | |
| Rpg1 | AAM81980 | LRR-PK | RLK | 7 | Stem rust | Avr-Rpg1 | P. graminis | [38] | |
| Mlo | CAB06083 | TM | Oth-R | 4 | Powdery mildew | E. graminis | [39] | ||
| S. lycopersicum (tomato) | Prf | AAC49408 | CNL | NBS | 5 | Bacterial speck | AvrPto | P. syringae | [40] |
| Mi | AAC67238 | CNL | NBS | 6 | Root knot | M. javanica | [41] | ||
| I2 | AAB63274 | NL | NBS | 11 | Fusarium wilt | Avr1 | F. oxysporum | [42] | |
| Ph-3 | AIB02970 | CNL | NBS | 9 | Late blight | P. infestans | [43] | ||
| Sw-5 | AAG31013 | CNL | NBS | 9 | Tomato spotted wilt | TSWV | [44] | ||
| Tm-2 | AAQ10735 | CNL | NBS | 9 | Tobacco mosaic | TMV | [45] | ||
| Bs4 | AAR21295 | TNL | NBS | 5 | Bacterial spot | AvrBs4 | X. campestris | [46] | |
| Hero | CAD29729 | CNL | NBS | 4 | Potato cyst | G. rostochiensis | [47] | ||
| Cf-2 | 2207203A | LRR-TM | RLP | 6 | Leaf mold | Avr2 | C. fulvum | [48] | |
| Cf-4 | CAA05268 | LRR-TM | RLP | 1 | Leaf mold | Avr4 | C. fulvum | [49] | |
| Cf-5 | AAC78591 | LRR-TM | RLP | 6 | Leaf mold | Avr5 | C. fulvum | [50] | |
| Cf-9 | CAA05274 | LRR-TM | RLP | 1 | Leaf mold | Avr9 | C. fulvum | [51] | |
| Ve1,2 | AAK58681.2 | LRR-TM | RLP | 9 | Verticillium wilt | V. dahliae | [52] | ||
| Hcr9-4E | CAA05269 | LRR-TM | RLP | 1 | Leaf mold | Avr4E | C. fulvum | [49] | |
| Fen | 2115395A | STK | Oth-R | 5 | Bacterial speck | AvrPto | P. syringae | [53] | |
| Pto | A49332 | STK | Oth-R | 5 | Bacterial speck | AvrPto | P. syringae | [54] | |
| Pti1 | NP_001233803 | STK | Oth-R | 12 | Bacterial speck | P. syringae | [55] | ||
| S. tuberosum (potato) | Rx | CAB50786 | CNL | NBS | 12 | PVX | PVX | [56] | |
| RB | Q7XBQ9 | CNL | NBS | 8 | Late blight | Avr1, Ipio, Ipib | P. infestans | [57] | |
| Rx2 | CAB56299 | LZ-NL | NBS | 5 | PVX | PVX | [58] | ||
| R1 | AAL39063 | LZ-NL | NBS | 5 | Late blight | Avr1 | P. infestans | [59] | |
| L. sativa (lettuce) | Rgc2 (Dm3) | Q9ZSD1 | NL | NBS | Downy mildew | Avr3 | B. lactucae | [60] | |
| P. nigrum (black pepper) | Bs2 | AAF09256 | CNL | NBS | Bacterial spot | AvrBs2 | X. campestris | [61] | |
| O. sativa (rice) | Xa1 | BAA25068 | NL | NBS | 4 | Bacterial blight | AvrXoo | X. oryzae | [62] |
| Pib | BAA76282 | CNL | NBS | 2 | Blast | M. grisea | [63] | ||
| Pi-ta | AAK00132 | NL | NBS | 12 | Blast | Avr-Pita | M. grisea | [64] | |
| Pi36 | ABI64281 | CNL | NBS | 8 | Blast | Avr-Pi36 | M. grisea | [65] | |
| Pia | BAK39926 | CNL | NBS | 11 | Blast | AvrPia | M. oryzae | [66] | |
| Pi-Kh | AAY33493 | NL | NBS | 11 | Blast | Avr-Pik | M. oryzae | [67] | |
| Pi37 | ABI94578 | NL | NBS | 1 | Blast | M. grisea | [68] | ||
| Xa5 | A2XZI2 | NL | NBS | 5 | Bacterial blight | AvrXa5 | X. oryzae | [69] | |
| Xa13 | ABD78944 | SET | Oth-R | 8 | Bacterial blight | AvrXa13 | X. oryzae | [70] | |
| Pi54 | CCD33085 | CNL | NBS | Blast | AvrPi54 | M. oryzae | [71] | ||
| Pi9 | ABB88855 | CNL | NBS | 6 | Blast | AvrPi9 | M. grisea | [72] | |
| Piz-t/Pi2 | ABC73398 | CNL | NBS | 6 | Blast | AvrPiz-t | M. grisea | [73] | |
| Rpr1 | BAA75812 | CNL | NBS | 11 | Blast | M. grisea | [74] | ||
| Pid3 | ACN62386 | CNL | NBS | 6 | Blast | M. grisea | [75] | ||
| Xa21 | AAC49123 | LRR-STK | RLK | 11 | Bacterial blight | AvrXa21 | X. oryzae | [76] | |
| Xa3/Xa26 | ABD36512 | LRR-STK | RLK | 11 | Bacterial blight | X. oryzae | [77] | ||
| CEBiP | BAE95828 | RLK | 3 | [78] | |||||
| Xa10 | AGE45112 | Oth-R | 11 | Bacterial blight | AvrXa10 | X. oryzae | [79] | ||
| Xa25 | AGS56390 | TM | Oth-R | 12 | Bacterial blight | X. oryzae | [80] | ||
| Xa27 | AEW90324 | LRR-TM | RLP | 6 | Bacterial blight | AvrXa27 | X. oryzae | [81] | |
| Pi-d2 | ACR15163 | B-lectin, STK | RLK | 6 | Blast | M. grisea | [82] | ||
| Z. mays (maize) | Rp1-D | AAD47197 | NL | NBS | 10 | Rust | P. sorghi | [83] | |
| Hm1 | Q41867 | 1 | Corn leaf blight | C. carbonum | [84] | ||||
| A. thaliana (Arabidopsis) | RPM1 | CAA61131 | CNL | NBS | 3 | Downy mildew | AvrB, AvrRpm1 | P. syringae | [85] |
| RPS2 | AAA21874 | NL | NBS | 4 | Downy mildew | AvrRpt2 | P. syringae | [86] | |
| RPP8/HRT | AAC83165 | CNL | NBS | 5 | Downy mildew | AvrRPP8 | P. parasitica | [87] | |
| RPP13 | AAF42832 | CNL | NBS | 3 | Downy mildew | ATR13 | P. parasitica | [88] | |
| RCY1 | BAC67706 | CNL | NBS | 5 | Mosaic type | CMV | [89] | ||
| RPP1 | AAC72977 | TNL | NBS | 3 | Downy mildew | ATR1 | P. parasitica | [90] | |
| RPP4 | AAM18462 | TNL | NBS | 4 | Downy mildew | P. parasitica | [91] | ||
| RPS4 | CAB50708 | TNL | NBS | 5 | Powdery mildew | AvrRps4 | P. syringae | [92] | |
| RPP5 | AAF08790 | TNL | NBS | 4 | Downy mildew | AvrRp5 | P. parasitica | [93] | |
| RPS5 | AAC26126 | NL | NBS | 1 | Downy mildew | AvrRphB | P. syringae | [94] | |
| RRS1 | ADM88042 | WRKY-TNL | NBS | 5 | Bacterial wilt | AvrRRS1 | R. solanacearum | [95] | |
| RPP27 | CAE51864 | LRR-TM | RLP | 1 | Downy mildew | P. parasitica | [96] | ||
| RFO1 | AAY86486 | LRR-STK | RLK | 1 | Fusarium wilt | F. oxysporum | [97] | ||
| PBS1 | AAG38109 | STK | Oth-R | 5 | AvrPphB | P. syringae | [98] | ||
| FLS2 | AED95370 | LRR-STK | RLK | 5 | Powdery mildew | AvrPto, AvrPtoB | P. syringae | [99] | |
| BAK1 | AT4G33430 | LRR-STK | RLK | 4 | AvrPto, AvrPtoB | P. syringae | [100] | ||
| NDR1 | AAB95208 | TM | Oth-R | 3 | AvrB, AvrRpt2 | P. syringae; P. parasitica | [101] | ||
| RPW8 | AAK09267 | RPW8 | Oth-R | 3 | Powdery mildew | E. cruciferarum | [102] | ||
| L. usitatissimum (flax) d | L6 | AAA91022 | TNL | NBS | 5 | Rust | AvrL6 | M. lini | [103] |
| L, L1-L11 | AAD25974 | TNL | NBS | 5 | Rust | AvrBs3 | M. lini | [104] | |
| M | AAB47618 | TNL | NBS | 8 | Rust | AvrM | M. lini | [105] | |
| P , P1-4 | AAK28806 | TNL | NBS | 14 | Rust | M. lini | [106] | ||
| B. vulgaris (sugar beet) | Hs1pro-1 | AAB48305 | LRR-TM | RLP | 1 | Beet cyst | H. schachtii | [107] | |
| N. tabacum (tobacco) | N | AAA50763 | TNL | NBS | Tobacco mosaic | TMV | [108] |
a: A. thaliana, Arabidopsis thaliana; B. vulgaris, Beta vulgaris; H. vulgare, Hordeum vulgare; L. sativa, Lactuca sativa; L. usitatissimum, Linum usitatissimum; N. tabacum, Nicotiana tabacum; O. sativa, Oryza sativa; P. nigrum, Piper nigrum; S. lycopersicum, Solanum lycopersicum; S. tuberosum, Solanum tuberosum; T. aestivum, Triticum aestivum; Z. mayes, Zea mayes; b: SET, sugar efflux transporter; TM, transmembrane; STK, serine/threonine protein kinase; c: PVX, potato virus X; B. graminis, Blumeria graminis; B. lactucae, Bremia lactucae; C. fulvum, Cladosporium fulvum; C. carbonum, Cochliobolus carbonum; E. cruciferarum, Erysiphe cruciferarum; E. graminis, Erysiphe graminis; F. oxysporum, Fusarium oxysporum; G. rostochiensis, Globodera rostochiensis; H. avenae, Heterodera avenae; H. schachtii, Heterodera schachtii; M. grisea, Magnaporthe grisea; M. oryzae, Magnaporthe oryzae; M. lini, Melampsora lini; M. javanica, Meloidogyne javanica; P. parasitica, Peronospora parasitica; P. infestans, Phytophthora infestans; P. syringae, Pseudomonas syringae; P. graminis, Puccinia graminis; P. sorghi, Puccinia sorghi; P. striiformis, Puccinia striiformis; P. triticina, Puccinia triticina; R. solanacearum, Ralstonia solanacearum; V. dahliae, Verticillium dahliae; X. campestris, Xanthomonas campestris; X. oryzae, Xanthomonas oryzae pv. oryzae (Xoo); CMV, cucumber mosaic virus; TMV, tobacco mosaic virus; TSWV, tomato spotted wilt virus; d: The chromosome numbers of genes were based on unpublished data.