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The biological mechanisms of MALAT1 in CRC. Resveratrol could suppress CRC cell invasion and migration by inhibiting Wnt/β-catenin signaling pathway through downregulating MALAT1; MALAT1 might promote CRC development via targeting AKAP-9; MALAT1 could bind to SFPQ and release PTBP2 from the SFPQ/PTBP2 complex that promotes tumor growth and migration.
