Table 4.
Comparison of MSSS values between carriers and noncarriers of genetic variants associated with MS severity.
| Group of Patients | Carriers | Noncarriers | Mann-Whitney p-Value | ||||
|---|---|---|---|---|---|---|---|
| No. of Persons (%) | MSSS, Mean ± SD | No. of Persons (%) | MSSS, Mean ± SD | ||||
| MIR499A*C/T | |||||||
| All persons | 170 (31.1) | 4.23 ± 1.92 | 376 (68.9) | 3.80 ± 1.98 | 0.0085 | ||
| Women | 123 (31.7) | 4.30 ± 1.97 | 265 (68.3) | 3.60 ± 1.93 | 0.0004 | ||
| Men | 47 (29.7) | 4.04 ± 1.80 | 111 (70.3) | 4.30 ± 2.03 | 0.57 | ||
| MIR499A*C | |||||||
| All persons | 188 (34.4) | 4.16 ± 1.93 | 358 (65.6) | 3.81 ± 1.98 | 0.028 | ||
| Women | 135 (34.8) | 4.19 ± 1.97 | 253 (65.2) | 3.62 ± 1.94 | 0.0039 | ||
| Men | 53 (33.5) | 4.11 ± 1.85 | 105 (66.5) | 4.28 ± 2.02 | 0.70 | ||
| MIR499A*C/T + MIR196A2*C | |||||||
| All persons | 147 (26.9) | 4.27 ± 1.93 | 399 (73.1) | 3.81 ± 1.97 | 0.0062 | ||
| Women | 108 (27.8) | 4.36 ± 1.96 | 280 (72.2) | 3.61 ± 1.93 | 0.0003 | ||
| Men | 39 (24.7) | 4.04 ± 1.85 | 119 (75.3) | 4.28 ± 2.00 | 0.61 | ||
| MIR499A*C + MIR196A2*C | |||||||
| All persons | 162 (29.7) | 4.20 ± 1.96 | 384 (70.3) | 3.82 ± 1.97 | 0.023 | ||
| Women | 118 (30.4) | 4.21 ± 1.98 | 270 (69.6) | 3.64 ± 1.94 | 0.0048 | ||
| Men | 44 (27.8) | 4.17 ± 1.91 | 114 (72.2) | 4.24 ± 1.99 | 0.92 | ||
Significant p-values are in bold.