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. 2015 Sep 24;14:152. doi: 10.1186/s12934-015-0337-y

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© Zhang et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Predicted products of engineered avermectin PKS. a AVE A1 of avermectin PKS. b AveDH2-KR2 in module 2 of avermectin PKS was replaced with MilDH2-ER2-KR2 of milbemycin PKS. c AveDH2-KR2 in module 2 and loading module AveLAT-ACP of avermectin PKS were replaced with MilDH2-ER2-KR2 of and loading module MilLAT-ACP of milbemycin PKS, respectively