(b).

Subjects	Radiological characteristics of subjects with CSF leakage
	Method of detection	Level of leakage	CSF scintigraphy	Early detection (in the bladder)	Meningeal enhancement (cranial MRI)	Subdural effusions (cranial MRI)
1	Intrathecal gadolinium enhanced MR myelography	C1/2, T12	Not detected	Yes	Yes	Yes
2	Intrathecal gadolinium enhanced MR myelography	L1/2, L2/3	n.d.	n.a.	n.d.	Yes
3	Intrathecal gadolinium enhanced MR myelography	C7/T1, T1/2	C7/T1	Yes	Yes	Yes
4	Intrathecal gadolinium enhanced MR myelography	C6/7, T1/2, T11, 12, L1/2, L3/4	L1/2, L3/4, T11/12	Yes	No	No
5	Intrathecal gadolinium enhanced MR myelography	C5/6, C6/7 (nerve root cysts L4/5, S2/3, S3)	Not detected	Yes	Yes	Yes
6	Intrathecal gadolinium enhanced MR myelography	C1/2, C5/6, C6/7, T12/L1	n.d.	n.a.	Yes	Yes
7	Intrathecal gadolinium enhanced MR myelography	(Weak) C4/5, T1/2	Not detected	Yes	No	Yes
8	Intrathecal gadolinium enhanced MR myelography	C7/T1, T1/2, T2/3	n.d.	n.a.	Yes	Yes
9	Intrathecal gadolinium enhanced MR myelography	C6/7, T1/2	n.d.	n.a.	Yes	Yes
10	MRI of the spine	Not detected (multiple nerve root cysts, 10 mm T1/2 and 25 mm S1/2)	S1/2	No	Yes	Yes