Table 2.
Overview of cerebrospinal fluid (CSF) and angiopoietin-2 (Ang-2) parameters. Q: quotient, that is, CSF to serum ratio; alb.: albumin; Ig: immunoglobulin; C: control subjects; LS: subjects with CSF leakage; LP: lymphocytic pleocytosis; N: normal; ABC: artificial blood contamination; n.a.: not applicable; and n.d.: not done.
| CSF characteristics | Ang-2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cell count per µL |
Cytology | CSF total protein (mg/L) | Qalb (CSF/serum × 103) |
Blood-CSF barrier function | IgG synthesis |
IgA synthesis |
IgM synthesis |
Oligoclonal bands | Lactate (mmol/L) |
QAng-2 (CSF/serum × 103) |
QAng-2/Qalb | |
| Subjects | LS | |||||||||||
|
| ||||||||||||
| 1 | 15.3 | LP | 1110 | 13.2 | Impaired | No | No | No | Type II | n.d. | 106.8 | 8.1 |
| 2 | 23.0 | LP | 896 | 8.8 | Impaired | No | No | No | Type I | 1.8 | 193.0 | 21.9 |
| 3 | 15.0 | LP | 1021 | 18.7 | Impaired | No | No | No | Type III | 1.7 | 403.6 | 21.6 |
| 4 | 1.3 | N | 476 | 5.9 | Intact | No | No | No | Type I | 1.6 | 203.6 | 34.5 |
| 5 | 0.3 | ABC | 2900 | 48.5 | n.a. | No | No | No | Type I | n.d. | 46.6 | 0.96 |
| 6 | 6.7 | LP | 365 | 4.8 | Intact | No | No | No | Type I | n.d. | 803.9 | 167.5 |
| 7 | 3.0 | N | 1033 | 15.4 | Impaired | No | No | No | Type I | 1.5 | 584.4 | 38.0 |
| 8 | 0.3 | ABC | 1044 | 17 | Impaired | n.a. | n.a. | n.a. | Type I | 1.8 | 418.6 | 24.6 |
| 9 | 2.0 | N | 729 | 9.9 | Impaired | No | No | No | Type I | 2.0 | 105.9 | 10.7 |
| 10 | 3.0 | N | 562 | 9.5 | Impaired | No | No | No | Type I | 1.7 | 542.4 | 57.3 |
|
| ||||||||||||
| Controls | C | |||||||||||
|
| ||||||||||||
| 1 | 0.7 | N | 404 | 5.3 | Intact | No | No | No | Type I | 1.7 | 218.3 | 41.5 |
| 2 | 1.0 | N | 413 | 6.3 | Intact | No | No | No | Type I | 1.9 | 235.8 | 37.7 |
| 3 | 2.3 | N | 796 | 14.8 | Impaired | No | No | No | Type I | 2.0 | 222.4 | 15.1 |
| 4 | 0.3 | N | 377 | 5.4 | Intact | No | No | No | Type I | 1.4 | 633.5 | 116.5 |
| 5 | 3.3 | N | 534 | 9.2 | Impaired | No | No | No | Type II | 1.7 | 254.4 | 27.5 |
| 6 | 0.3 | N | 654 | 10.1 | Impaired | No | No | No | Type I | 2.9 | 332.5 | 32.8 |
| 7 | 1.0 | ABC | 236 | 3.5 | Intact | No | No | No | Type I | 1.8 | 175.3 | 50.4 |
| 8 | 1.3 | N | 345 | 5.7 | Intact | No | No | No | Type I | 1.5 | 243.5 | 43.1 |
| 9 | 3.3 | N | 338 | 4.4 | Intact | No | No | No | Type I | 1.6 | 443.1 | 101.4 |
| 10 | 0.3 | N | 506 | 7.2 | Intact | No | n.d. | No | Type I | 1.3 | 371.0 | 51.5 |