Table 2.
Effects of anti-miR-10b on cisplatin-induced cell growth inhibition in CD44v3highALDH1high cells following 200 kDa-HA treatment.
| Treatments | Cisplatin-induced tumor cell growth inhibition IC50 (µM)* (% of control) |
|---|---|
| Negative miRNA control-treated cells (control) (No HA) | 2.00 ± 0.15 (100.00%) |
| Negative miRNA control-treated cells (+200 kDa-HA) | 5.75 ± 0.14 (288.00%) |
| Anti-miR-10-treated cells (No HA) | 1.58 ± 0.22 (0.79%) |
| Anti-miR-10b-treated cells (+200 kDa-HA) | 1.58 ± 0.23 (0.79%) |
*Tumor cell growth inhibition (IC50) is designated as “the µM concentration of chemotherapeutic drug (e.g., cisplatin treatment) that causes 50% inhibition of tumor cell growth” using CellTiter-Glo Luminescent Cell Viability Assay as described in Section 2. IC50 values are presented as the means ± standard deviation. All assays consisted of at least six replicates and were performed on at least 3–5 different experiments.