Table 2.
Transcription factor binding sites enriched in differentially methylated loci
| Transcription factor | Genes in Overlap | Motif |
|---|---|---|
| MGUS | ||
| ARNT | 202 | NDDNNCACGTGNNNNN |
| ATF6 | 95 | TGACGTGG |
| E47 | 205 | VSNGCAGGTGKNCNN |
| USF | 203 | NNRNCACGTGNYNN |
| LXR | 55 | TGGGGTYACTNNCGGTCA |
| TCF1P | 184 | GKCRGKTT |
| New MM | ||
| PAX2 | 36 | NNNNGTCANGNRTKANNNN |
| GATA | 161 | WGATARN |
| MEF2 | 21 | NNTGTTACTAAAAATAGAAMNN |
| E2F | 56 | TWSGCGCGAAAAYKR |
| CACCC BINDING FACTOR | 205 | CANCCNNWGGGTGDGG |
| Relapsed MM | ||
| STAT3 | 113 | NNNTTCCN |
| PAX4 | 193 | NAAWAATTANS |
| EGR3 | 56 | NTGCGTGGGCGK |
| EVI1 | 44 | AGATAAGATAA |
| HNF6 | 189 | HWAAATCAATAW |
| MAZ | 135 | GGGGAGGG |
| SREBP1 | 136 | NATCACGTGAY |