Table 1.
General and Disease Characteristics of Cases With Hodgkin Lymphoma and Controls, Scandinavian Lymphoma Etiology Study, 1999–2002
Characteristic | No. of Control Subjects (n = 3,187) | Total No. of HL Casesa (n = 585) | No. With Nodular Sclerosis HL (n = 409) | No. With Mixed-Cellularity HL (n = 102) | No. of Other and Unclassified HL (n = 74) | No. With EBV-Positive HL (n = 142) | No. With EBV-Negative HL (n = 356) |
---|---|---|---|---|---|---|---|
Age, years | |||||||
18–34 | 312 | 277 | 211 | 41 | 25 | 58 | 182 |
35–54 | 861 | 171 | 121 | 25 | 25 | 37 | 112 |
55–74 | 2,014 | 137 | 77 | 36 | 24 | 47 | 62 |
Sex | |||||||
Male | 1,767 | 305 | 202 | 66 | 37 | 91 | 166 |
Female | 1,420 | 280 | 207 | 36 | 37 | 51 | 190 |
Country | |||||||
Denmark | 1,186 | 247 | 170 | 40 | 37 | 64 | 144 |
Sweden | 2,001 | 338 | 239 | 62 | 37 | 78 | 212 |
Rheumatoid arthritisb | |||||||
No | 3,073 | 559 | 395 | 93 | 71 | 134 | 345 |
Yes | 88 | 21 | 11 | 7 | 3 | 8 | 7 |
Psoriasisb | |||||||
No | 3,002 | 555 | 390 | 97 | 68 | 135 | 338 |
Yes | 150 | 25 | 17 | 3 | 5 | 7 | 14 |
Type I diabetesb | |||||||
No | 3,021 | 577 | 405 | 100 | 72 | 141 | 351 |
Yes | 140 | 6 | 3 | 1 | 2 | 1 | 4 |
Allergic rhinitisb | |||||||
No | 2,340 | 429 | 294 | 79 | 56 | 107 | 261 |
Yes | 815 | 150 | 111 | 21 | 18 | 34 | 91 |
Childhood eczemab | |||||||
No | 2,935 | 521 | 360 | 96 | 65 | 129 | 318 |
Yes | 202 | 58 | 43 | 6 | 9 | 12 | 35 |
Asthmab | |||||||
No | 2,896 | 534 | 376 | 92 | 66 | 131 | 325 |
Yes | 275 | 50 | 32 | 10 | 8 | 11 | 30 |
IgE reactivityb | |||||||
Negative | 1,714 | 388 | 264 | 73 | 51 | 92 | 238 |
Positive | 372 | 122 | 91 | 19 | 12 | 29 | 75 |
IgE reactivity before treatment or in controlsb | |||||||
Negative | 1,714 | 131 | 87 | 27 | 17 | 26 | 86 |
Positive | 372 | 53 | 36 | 11 | 6 | 12 | 35 |
IgE reactivity during treatment or in controlsb | |||||||
Negative | 1,714 | 158 | 117 | 27 | 14 | 40 | 98 |
Positive | 372 | 41 | 33 | 5 | 3 | 9 | 25 |
Self-reported hay fever and positive IgE reactivity before treatment or in controlsb | |||||||
Negative | 1,834 | 146 | 97 | 30 | 19 | 30 | 96 |
Positive | 233 | 37 | 25 | 8 | 4 | 8 | 25 |
Abbreviations: EBV, Epstein-Barr virus; HL, Hodgkin lymphoma; IgE, immunoglobulin E.
a Diseases with fewer than 5 cases are not presented.
b Numbers do not add up to the total number of participants because some questions were left unanswered or, for IgE reactivity analyses, not all participants gave a blood sample (75 cases, 1,101 controls).