Table 2. General information about gene expression in paired males exposed to PZQ compared with no-drug controls.

S. mansoni genes	Expressed genes a	Paired Males
		Diff. expressed b	Down-regulated	Up-regulated
Detected on the microarrays	9,977	1,120	592	528
Predicted in the genome	7,039	709	378	331
Not predicted in the genome c	2,938	411	214	197

^a Number of genes expressed in at least one condition, i.e. in control or in treated paired male adult worms.

^b q-value < 5%

^c Either predicted in S. japonicum, present in other species, or detected only in S. mansoni without close homologs in other species (no match).