Table 2. Burden of off-target infections averted by annual ivermectin mass treatment with ivermectin in Africa.
Burden averted by ivermectin mass treatment (DALYs x 1,000) a | ||||||||
---|---|---|---|---|---|---|---|---|
Country | Ascariasis | Trichur-iasis | Hook-worm | Strongy-loidiasis | Lymphatic filariasis | Scabies | Total | (%) |
Angola | 0.2 | 0.1 | 0.2 | 0.1 | 0.2 | 0.2 | 0.9 | (0.2%) |
Burundi | 0.4 | 0.1 | 1.3 | 0.7 | 0.8 | 1.2 | 4.6 | (0.9%) |
Cameroon | 23.6 | 6.1 | 5.7 | 7.2 | 8.5 | 8.0 | 59.3 | (12%) |
Central African Republic | 0.5 | 0.2 | 4.3 | 0.3 | 2.6 | 3.0 | 10.9 | (2.2%) |
Chad | 0.1 | 0.0 | 3.2 | 2.1 | 1.8 | 8.6 | 15.8 | (3.2%) |
Congo | 1.5 | 0.8 | 0.6 | 0.5 | 0.8 | 0.8 | 5.1 | (1%) |
Democratic Republic of Congo | 18.1 | 5.5 | 11.9 | 1.6 | 11.0 | 14.0 | 62.0 | (12.6%) |
Equatorial Guinea | 0.1 | 0.1 | 0.0 | 0.0 | 0.1 | 0.0 | 0.3 | (0.1%) |
Ethiopia | 2.6 | 1.7 | 2.5 | 0.1 | 2.2 | 8.0 | 17.2 | (3.5%) |
Liberia | 1.1 | 0.5 | 3.0 | 3.7 | 2.0 | 2.9 | 13.2 | (2.7%) |
Malawi | 0.3 | 0.0 | 0.7 | 2.6 | 0.4 | 5.3 | 9.2 | (1.9%) |
Nigeria | 112.0 | 1.2 | 20.5 | 45.3 | 31.8 | 49.1 | 259.9 | (52.8%) |
Sudan and South Sudan b | 0.1 | 0.0 | 0.9 | 1.9 | 0.6 | 5.5 | 9.0 | (1.8%) |
Uganda | 0.6 | 0.2 | 3.3 | 3.4 | 2.0 | 4.2 | 13.8 | (2.8%) |
United Republic of Tanzania | 0.2 | 0.5 | 2.9 | 1.2 | 1.8 | 4.9 | 11.5 | (2.3%) |
Total | 161.5 | 16.9 | 61.0 | 70.9 | 66.6 | 115.7 | 492.5 | (100%) |
a These figures are the product of the potential disease burden due to off-target infections in people treated with ivermectin and the assumed effect of ivermectin treatment on the disease burden (see Box 1).
b Estimates for Sudan and South Sudan are merged, as information on the burden per capita was reported for the two together [14].