Table 3. Secondary outcomes.
Change in proximal total gastric volume and proximal to distal total gastric volume ratio after ingesting a liquid meal (400 mL, 200 kcal) among the DA-9701 group (n = 18) and the placebo group (n = 19).
| Variables | DA-9701 group (n = 18) | Placebo group (n = 19) | a Mean difference (95% CI) | P-value |
|---|---|---|---|---|
| Proximal TGV, mL | ||||
| Pre-test meal | 90.6 ± 27.3 | 104.2 ± 32.0 | ||
| 15 min after test meal | 386.0 ± 43.2 | 396.4 ± 42.2 | ||
| b Adjusted proximal TGV at 15 min, mL (LSM ± SE) | 389.9 ± 9.5 | 392.7 ± 9.3 | −2.9 (−30.3 to 24.5) | 0.832 |
| Proximal to distal TGV ratio | ||||
| Pre-test meal | 1.93 ± 0.40 | 2.33 ± 0.74 | ||
| 15 min after test meal | 4.14 ± 1.26 | 3.59 ± 1.38 | ||
| c Adjusted proximal to distal TGV ratio at 15 min, mL (LSM ± SE) | 4.33 ± 0.29 | 3.40 ± 0.29 | 0.93 (0.08 to 1.79) | 0.034 |
CI, confidence interval; TGV, total gastric volume; LSM, least squares mean
a Differences in proximal TGV and proximal to distal TGV ratio between the DA-9701 and the placebo group 15 min after the test meal
b Estimated from analysis of covariance adjusted for value of proximal TGV at the pre-test meal after normality checking (P > 0.05)
c Estimated from analysis of covariance adjusted for value of proximal to distal TGV ratio at the pre-test meal after normality checking (P > 0.05)