Table 1. Characteristics of SLE patients and healthy controls.
| SLE patients | Healthy controls | |
|---|---|---|
| No. of individuals | 45 | 40 |
| Average age (years) [range] | 38.4 [22–65] | 38.5 [25–72] |
| % females | 96 | 78 |
| % ANA-positive | 80 | 7.5 |
| % dsDNA antibody-positive | 47 | 5 |
| % Rheumatoid factor-positive | ||
| IgM | 16 | ND |
| IgA | 18 | ND |
| Average amount of Ig’s (g/L) [range]: | ||
| IgG | 12.5 [5.8–24.1] | 12.1 [8.3–18.7] |
| IgA | 2.6 [<0.05–6.5] | 2.7 [1.0–5.2] |
| IgM | 1.1 [0.2–5.5] | 1.7 [0.6–4.2] |
| % on immunosuppressive medication | 67 | 0 |
| Average C-reactive protein (mg/L) [range] | 3.9 [0–21] | ND |
| % with low C3 | 51 | ND |
| % with low C4 | 67 | ND |
| Average serum creatinine (mg/dl) | 0.61 | ND |
| Average eGFR (ml/min/1.73m2) | 117.38 | ND |
| Average disease duration (years) [range] | 10 [0–24] | ND |
| Average SLEDAI score [range] | 4.7 [0–21] | ND |
SLE—systemic lupus erythematosus, SLEDAI—SLE disease activity index, ANA- nuclear antibodies, dsDNA—double stranded DNA, Ig—immunoglobulin, eGFR—estimated glomerular filtration rate, ND—not determined.