Predicted signaling pathways mediating the effects of miR-92a on chondrogenesis and cartilage degeneration. Predicted potential target genes of miR-92a are indicated by the red boxes. (A) PI3K-Akt, (B) ErbB and (C) focal adhesion signaling pathways were predicted based on the potential target genes of miR-92a. miR-92a, microRNA-92a; PI3K, phosphoinositide-3 kinase; mTOR, mammalian target of rapamycin. Predicted signaling pathways mediating the effects of miR-92a on chondrogenesis and cartilage degeneration. Predicted potential target genes of miR-92a are indicated by the red boxes. (D) ECM-receptor interaction and (E) mTOR signaling pathways were predicted based on the potential target genes of miR-92a. miR-92a, microRNA-92a; PI3K, phosphoinositide-3 kinase; mTOR, mammalian target of rapamycin.