Figure 3.

Morphological alterations in liver mitochondria during ALF. Control group, the mitochondria were round or oval with complete membrane structures and concentric circles or longitudinally arranged ridges that were tidy and compact; ALF 4 h, the mitochondria were reduced in number, fairly structured, relatively complete and had a complete structure of ridges that had a relatively tidy arrangement but with concentrated stroma; ALF 8 h, the mitochondria were swollen and clearly damaged but had somewhat complete outer membranes and disorganized ridge structures; ALF 12 h, the mitochondria were clearly swollen and their inner structures were not easily visible; ALF 24 h, the outer membrane was disrupted and the mitochondria had collapsed. ALF, acute liver failure.