. 2015 Jul 2;12(4):5035–5041. doi: 10.3892/mmr.2015.4029

Table I.

Alterations in serum ALT, AST, TBIL, PT and PTA in the liver of D-GalN/LPS-treated rats.

Group	ALT (U/l)	AST (U/l)	TBIL (µmol/l)	PT (sec)	PTA (%)
Control	40.05±3.93	132.89±19.62	1.41±0.77	9.68±0.83	112.69±13.06
ALF 4 h	121.25±52.33^a	315.84±106.46^a	1.54±0.87	16.28±4.93^a	66.44±24.23^a
ALF 8 h	827.18±359.48^a	2489.06±1181.33^a	6.76±3.63^a	19.55±6.93^a	58.88±20.12^a
ALF 12 h	7778.60±4026.25^a	9461.90±5238.06^a	52.71±10.43^a	41.35±12.61^a	27.96±9.99^a
ALF 24 h	73.28±31.92^b	116.08±12.18	64.23±5.59^a	71.99±21.55^a	15.60±4.44^a

P<0.01, compared with the control group;

P<0.05, compared with the control group. ALT, alanine aminotransferase; AST, aspartate amino-transferase; TBIL, total bilirubin; PT, prothrombin time; PTA, prothrombin activity; D-GalN, D-galactosamine; LPS, lipopolysaccharide; ALF, acute liver failure.