(A) Oxidized low-density lipoprotein (oxLDL) induces phenotypic changes in human umbilical smooth muscle cells (HUSMCs), and increases the expression levels of galectin-3 (gal-3). The cells were treated with various concentrations of oxLDL (0-50 μg/ml) for 48 h, and the expression levels of gal-3, calponin, smooth muscle α-actin (SMA), and osteopontin (OPN) were measured by western blotting. (B) The protein expression levels of GAPDH were used as a control. The respective densitometric measurement results are given, and the band intensities of the HUSMCs were defined by the control and set to 1. Data are presented as the mean ± standard deviation. *P<0.05, vs. the control.