Table 3.

Estimates of slope over 96 h with log-transformed cytokines measured in initial dialysate samples from at least 8 of 10 study patients

Cytokine	Brain interstitial fluid				Serum
	Slope	p value	Lowera	Upperb	Slope	p value	Lowera	Upperb
IL-8	−0.013	0.002	−0.02	−0.006	0.006	0.054	0	0.012
IP-10	−0.009	0.014	−0.016	−0.002	−0.001	0.245	−0.003	0.001
MCP-1	−0.014	<0.001	−0.02	−0.008	0	0.557	−0.001	0.002
MIP-1β	−0.013	<0.001	−0.018	−0.008	−0.001	0.029	−0.002	0
IL-6c	−0.013	0.002	−0.02	−0.006	0.065, 0.013	0.004	0.03	0.1
						0.01	−0.02	−0.005
IL12p40p70	−0.015	0.026	−0.027	−0.002	0	0.573	0	0.001
IL-1RA	−0.005	0.073	−0.01	0.001	−0.001	0.493	−0.003	0.002
MIP-1α	−0.013	0.002	−0.02	−0.006	0.001	0.429	−0.002	0.005
RANTES	−0.015	0.101	−0.034	0.004	−0.005	0.400	−0.02	0.01
IFN-α	−0.01	0.043	−0.02	0	0.001	0.109	0	0.002
G-CSF	−0.021	0.049	−0.042	0	−0.001	0.452	−0.004	0.002
IL-2R	−0.025	0.044	−0.05	−0.001	0	0.808	−0.001	0.001
VEGF	−0.005	0.002	−0.007	−0.003	0	0.761	−0.004	0.005
IL-17	−0.008	0.110	−0.019	0.003	−0.001	0.367	−0.003	0.001
IL-10	−0.006	0.145	−0.016	0.003	−0.003	0.185	−0.009	0.002
MIG	−0.014	0.215	−0.04	0.012	−0.003	0.164	−0.007	0.003
IFN-γ	−0.013	0.264	−0.037	0.012	0.01	0.411	−0.002	0.003

n/a Insufficient patient data (n<2) for analysis

^aLower boundary for the 95 % confidence interval

^bUpper boundary for the 95 % confidence interval

^cFor IL-6 serum only, the results are presented for the two-phase linear regression. The first row represents 0–12 h, and the second row represents 12–96 h. The p values and 95 % confidence intervals of the slopes of the two lines are presented