Table 1. Resting Metabolic Rate and Respiratory Quotient.

Author/year	Population/N	MG1 RQ2	Measured mean RQ	RMR3 (REE) mean kcal/day	Primary outcome
Alam et al12 2005	Healthy women n=37	0.85	0.83	MG session 1=1390 MG session 2=1390 DTC4 session 1=1278 DTC session 2=1235	Reproducibility and validity for RMR of the MG using the DTC as a reference.
Compher et al13 2005	Home nutrition support patients. n=24	0.85	0.77	MG session 1=1302 MG session 2=1296 DTC (only 1 session)= 1446	Reproducibility of the MG in a clinical population compared with the DTC.
Cooper et at21	Healthy Adults n=38	0.85	N/A	N/A	MedGem was not valid compared to the DTC.
Fares et al20 2008	Healthy adults. n=48	0.85	N/A	MG =1489 GEM=1149 **	Validity and acceptability of MG for measurement of REE in older adults.
Fields et al14 2006	Healthy children. n=100	0.85	N/A	MG =1452 ** DTC =1349	Assess the validity of the MG in children.
Hlynsky et al15 2005	Anorexia nervosa patients vs healthy adults n=27	0.85	Anorexia=0.9 Healthy=0.78	MG anorexia =1243 MG healthy = 1398 DTC anorexia = 1369 DTC healthy = 1519	Compare the MG with the DTC to determine if the tests agree
Reeves, et al16 2004	Cancer Patients vs healthy adults n=35	0.85	Cancer=0.71 Healthy=0.72	MG cancer=1351 * MG healthy=1258 VMax6 cancer=1526 VMax healthy=1371	Compare measurements of REE using the MG device and VMax in pts with cancer vs. healthy subjects.
Rubenbauer et al17 2006	Healthy adults. n=19	0.85	REE=0.83 FEE7=0.87 AEE8=0.88	MG REE=1551 Physiodyne REE=1552 MG FEE=1825 Physiodyne FEE=1875 MG AEE=3489 Physiodyne AEE=3333	Determine how closely the MG compared with the Physiodyne in 3 different physiologic conditions.
Stewart et al18 2005	Healthy adults n=50	0.85	N/A	Mean difference in RMR=4.66±113.4 kcal/day	Compare simultaneous measurements of RMR with MG and DTC
St-Onge, et al19 2004	Healthy adults n=15	0.85	N/A Food quotient provided was similar to RQ of MG	MG REE=1543 DTC REE=1546 MG MEE9=1619 DTC MEE=1678 MG PE EE10=1630 DTC PE EE=1697	Determine if the MG can measure post-prandial energy expenditure compared with DTC

¹MG = MedGem

²RQ = Respiratory quotient

³RMR (REE) = Resting metabolic rate (Resting energy expenditure)

⁴DTC = Deltatrac

⁵GEM = Europa Gas Exchange monitor

⁶VMax = Vmax Encore 29

⁷FEE = Fed energy expenditure

⁸AEE = Activity energy expenditure

⁹MEE = Measured energy expenditure

¹⁰PP EE = Post-prandial energy expenditure

^*p<0.05 only for MG vs Vmax in patients with cancer

^**p<0.001