Table 2.
Clinicopathologic features of patients with collecting duct carcinoma, disease relapses and salvage treatments
| No | Age | Sex | ECOG score | pT | Tumour size, cm | LR | Time to LR, months | DM | Time to DM, months | Salvage treatment | OS, months |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 48 | M | 0 | pT1b | 6.0 | + | 10.0 | + | 12.4 | LR-Surgery, DM-CHT: 3xGC, PD, 3xdocetaxl | 21.5 DD |
| 2 | 55 | M | 1 | pT3a | 7.5 | - | + | BN | RT-bones | 3 DD | |
| 3 | 76 | M | 1 | pT3b | 6.0 | - | + | 15.1 | CHT: 5xGC, PD | 24.2 DD | |
| 4 | 62 | M | 1 | pT3b | 6.0 | - | + | 8.1 | Surgery - spermatic cord | Lost to FU | |
| 5 | 61 | M | 1 | pT3b | 10.0 | + | 7.9 | - | RT (30Gy), SD (4 months), PD, CHT: 2xGC, PD, 2xdoxorubicin | 21.2 DD | |
| 6 | 63 | M | 2 | pT3b | 8.0 | - | + | BN | RT-bones, CHT:2xGC, renal toxicity, 1xDoxorubicin | 7.2 DD | |
| 7 | 60 | F | 1 | pT1b | 6.0 | + | 1.9 | + | 7.9 | LR-RT (50Gy), PR (3 months), DM, CHT:6xGC, PR (5 months), PD, Surgery (liver) | 24.3 DD |
| 8 | 83 | M | 2 | pT3a | 11.0 | - | + | BN | - | 1.5 DD | |
| 9 | 64 | M | 1 | pT2a | 9.0 | + | 1.6 | + | 1.6 | - | 2.0 DD |
| 10 | 73 | F | 3 | pT3a | 3.0 | - | + | BN | RT-bones (BN), CHT:3xGC | 4.2 DD |
ECOG: Eastern Cooperative Oncology Group; LR: local recurrence; DM: distant metastases; OS: overall survival; M: male; F: female; BN: before nephrectomy; CHT: chemotherapy; DD: died of disease; FU: follow-up; GC: platinum salts+gemcitabine; PD: progressive disease; PR: partial response; RT: radiotherapy; SD: stable disease.