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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: J Thorac Oncol. 2015 Oct;10(10):1383–1395. doi: 10.1097/JTO.0000000000000654

Fig. 3.

Fig. 3

Conventional type A thymoma versus atypical type A thymoma variant. A. Conventional type A thymoma exhibiting areas composed of spindle cells (upper half) and polygonal cells (lower half) separated by a broad fibrouis septum. B. and C. Atypical type A thymoma variant showing various degrees of spontaneous necrosis in polygonal cell areas. This tumor invaded the lung and showed a missense mutation (chromosome 7 c.74146970T>A) in the GTF2I gene that is common in type A thymomas but rare in type B thymomas and thymic carcinomas.23