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. Author manuscript; available in PMC: 2016 Oct 5.
Published in final edited form as: Vaccine. 2015 Aug 28;33(41):5386–5395. doi: 10.1016/j.vaccine.2015.08.062

Figure 5. Vaccination with VLPV-PSA delays tumor growth at early time-points.

Figure 5

Mice were immunized with VLPV-PSA vaccine twice with 4 weeks interval between primary and secondary immunizations. Four weeks after secondary immunization mice were s.c. injected with TRAMP-PSA tumor cells. Tumor growth was monitored weekly for up to 15 weeks. Combined results from 4 independent experiments with identical trend are shown (n=62 for the control group, n=57 for the vaccine group). Time-to-event analysis (tumor base of 100 mm2) was performed by the Gehan-Breslow test (p value is shown on the graph). The results of the individual experiments are shown in Table 1.