Table 1.
Comparison of baseline characteristics for uveitic eyes of patients completing or not completing the 54 month visit, in the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study*
| Completed 54 month visit | Did not complete 54 month visit | P-value** | |
|---|---|---|---|
| Characteristics of Patients | N = 213 | N = 42 | |
| Age (years), Mean (Standard Deviation) | 46 (14) | 47 (19) | 0.83 |
| Female, N(%) | 158 (74%) | 33 (79%) | 0.55 |
| Race/Ethnicity, N(%) | |||
| White | 122 (57%) | 20 (48%) | 0.17 |
| Hispanic | 26 (12%) | 7 (17%) | |
| Black | 56 (26%) | 10 (24%) | |
| Other | 9 (4%) | 5 (12%) | |
| Duration of uveitis (years), median (25th–75th percentile (IQR)) | 3.9 (1.4, 8.1) | 3.4 (0.7, 6.8) | 0.17 |
| Bilateral uveitis, N(%) | 188 (88%) | 36 (86%) | 0.64 |
| Site of uveitis, N(%) | |||
| Intermediate | 86 (40%) | 11 (26%) | 0.08 |
| Posterior or Panuveitis | 127 (60%) | 31 (74%) | |
| Associated systemic inflammatory disease, N(%) | 55 (26%) | 14 (33%) | 0.32 |
| Bone density, N(%) | |||
| Normal | 109 (52%) | 23 (58%) | 0.71 |
| Osteopenia | 84 (40%) | 15 (38%) | |
| Osteoporosis | 17 (8%) | 2 (5%) | |
| Characteristics of Eyes‡ | E = 401 | E = 78 | |
| Eye-specific duration of uveitis (years), median (IQR) | 3.8 (1.3, 8.0) | 3.4 (0.7, 6.9) | 0.24 |
| Visual acuity, median (IQR), letters | 69 (52, 80) | 73 (41, 82) | 0.70 |
| Visual acuity 20/40 or better | 196 (49%) | 42 (54%) | 0.40 |
| Visual acuity 20/200 or worse | 56 (14%) | 18 (23%) | 0.16 |
| Visual field sensitivity (mean deviation), median (IQR), decibels | −5.0 (−9.3, −3.0) | −5.8 (−13.2, −2.7) | 0.19 |
| Active uveitis, N(%) | 311 (79%) | 62 (79%) | 0.99 |
| Anterior chamber cells, N(%) | |||
| 0 | 213 (53%) | 27 (35%) | 0.28 |
| 0.5+ | 112 (28%) | 25 (32%) | |
| 1+ or more | 76 (19%) | 26 (33%) | |
| Vitreous haze, N(%) | |||
| 0 | 124 (33%) | 17 (22%) | 0.46 |
| 1+ | 167 (45%) | 38 (50%) | |
| 2+ or more | 80 (22%) | 21 (28%) | |
| Lens opacities, N(%) | |||
| Absent | 90 (22%) | 16 (21%) | 0.87 |
| Present | 142 (35%) | 24 (31%) | |
| Aphakic or pseudophakic | 169 (42%) | 38 (49%) | |
| Intraocular pressure (mm Hg), median (IQR) | 14 (11.5, 17) | 14 (11.5, 17) | 0.82 |
| Macular edema (center point thickness > 240 m), N (%) | 125 (35%) | 30 (41%) | 0.48 |
*
For covariates where the counts do not add up to the total, the remaining observations are missing.
N=number of eyes.
**
P-values are calculated using the χ2 or Fisher’s exact text (categorical covariates) and Wilcoxon rank sum (continuous covariates) for the person-level covariates. P-values are calculated using GEE with exchangable covariance structure to account for two eyes from the same person for the eye-level covariates.
‡
Eye specific characteristics are summarized for the 479 eyes with uveitis at enrollment.